Infectious Disease

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Treatment for C difficile Shows Promising Potential in First-in-Human Phase 1 Trial
A first-in-human trial evaluating the safety, pharmacokinetics, and fecal microbiome effects of a novel DNA polIIIC inhibitor demonstrated the antibacterial’s promise as a potential treatment alternative to vancomycin for the treatment of Clostridioides difficile.
NFID Urges Public to Receive Influenza and Pneumococcal Disease Vaccinations
The NFID released data that revealed only 52% of adults in the country plan to get vaccinated against the flu this season.
FDA Approves New Antibiotic for Community-Acquired Bacterial Pneumonia
Lefamulin (Xenleta, Nabriva Therapeutics) is the first IV and oral antibiotic with a novel mechanism of action approved by the FDA in nearly 2 decades, according to Nabriva.
Risks of Rocky Mountain Spotted Fever Examined
A binational team of investigators at the University of California, Davis, has conducted the first comprehensive study to examine the risk factors for Rocky Mountain spotted fever in Mexicali, Mexico. They found that citywide, just 1 in 1000 ticks was infected with the disease, but in certain neighborhoods, about 1 in 10 ticks was infected.
New Treatment for Certain Bacterial Pneumonia Receives FDA Approval
Ceftolozane and tazobactam was initially approved by the FDA in 2014 o treat complicated intra-abdominal infections and for complicated urinary tract infections.
How Early Identification of Community-Acquired Pneumonia Can Lead to Positive Outcomes
Brown Bagging is an essential educational and safety tool for helping treat community-acquired pneumonia. 
Robust Responses Found in 20-Serotype Pneumococcal Vaccine Trial
The study presented at the 29th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) in Amsterdam, Netherlands was a phase 2 randomized, active-controlled, double-blinded trial (N=444). All participants were ages 60 to 64 years.
Pneumonia Prevention Is Possible
A triad of techniques can reduce the likelihood of infection, and pharmacy teams can help patients with all of them.
Pharmacist-Tech Teams Increase Immunization Rates in Elders
The CDC has declared immunizations one of the greatest health achievements of the 20th century, but vaccination rates among adults remain suboptimal.
FDA Approves Premixed Vancomycin Injection
Officials with the FDA have approved Xellia Pharmaceuticals’ Premixed Vancomycin Injection in a Ready-to-Use (RTU) bag, according to the company.
HIV Increases Mortality Risk in Patients With Hepatocellular Carcinoma
HIV-positive patients with hepatocellular carcinoma had an adjusted 24% increased hazard of death compared to their HIV-negative peers.
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